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Some people notice a metallic or off taste, foods they used to love losing their appeal, or Bruising and Injection Site Reactions on Semaglutide Bruising and mild injection site reactions, meaning redness, a small lump, itching, or tenderness, are common with subcutaneous semaglutide and are usually harmless

Such intercurrent events will likely result in different placebo-adjusted treatment effects than if they had not occurred and raise questions about how these events should be accounted for and how trial results should be interpreted (Table 1)

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